When packaging has a Green Dot, we know: That's garbage for the yellow garbage can. The waste disposal system in our cells works in a similar way. If a protein is no longer usable, a short protein piece called "ubiquitin" is attached to it and it is disposed of. When protein garbage accumulates in cells, tumors develop. Meanwhile, medicine can individually address such defects in patients' molecular profiles, for diseases such as cancer and immune disorders. This medical progress raises some bioethical questions. Biochemist and Nobel laureate Aaron Ciechanover engrossingly discusses the opportunities and bioethical issues of "personalized medicine" and shows how his research is contributing to the development of new therapies.
Aaron Ciechanover, born in Haifa in 1947, is a professor at the Faculty of Medicine at the Technion - Israel Institute of Technology. In 2004, he received the Nobel Prize in Chemistry together with Avram Hershko and Irwin Rose for the discovery of ubiquitin-directed protein degradation.
Introduction: Sebastian Schuck, Professor of Biochemistry and Molecular Cell Biology at the University of Heidelberg, Germany
In the framework of the International Science Festival - Geist Heidelberg
Geist Heidelberg Lecture
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