If packaging has a green dot, we know: This is waste for the yellow garbage can. Waste disposal in our cells works in a similar way. If a protein is no longer usable, a short piece of protein called "ubiquitin" is attached to it and it is disposed of. When the protein waste accumulates in the cells, tumors develop. Medicine can now respond individually to such errors in the molecular profile of patients, for example in diseases such as cancer and immune disorders. This medical progress raises a number of bioethical questions. The biochemist and Nobel Prize winner Aaron Ciechanover discusses the opportunities and bioethical issues of "personalized medicine" in a captivating way and shows how his research contributes to the development of new therapies.
AaronCiechanover, born in Haifa in 1947, is a professor at the medical faculty of the Technion - Israel Institute of Technology. Together with Avram Hershko and Irwin Rose, he was awarded the Nobel Prize in Chemistry in 2004 for his discovery of ubiquitin-controlled protein degradation.
Introduction: Sebastian Schuck, Professor of Biochemistry and Molecular Cell Biology at the University of Heidelberg
As part of the International Science Festival - Geist Heidelberg
Medicine made to measure
Due to the current situation in Israel and the associated travel warnings and flight cancellations, the Israeli Nobel Prize winner Aaron Ciechanover unfortunately has to postpone his planned lecture with us. We will announce an alternative date as soon as possible. Tickets that have already been purchased remain valid or can be returned to the respective advance booking office where they were purchased. We thank you in advance for your understanding.