Organoids to Model Human Disease
The historical dependence of biological research on the use of animal models has sometimes made it difficult to answer questions specific to understanding human biology and disease.
Human organoids - laboratory-grown organ-like cell cultures derived from stem cells - are now revolutionizing medical research by making it possible to recreate in detail the architecture and physiology of human organs. They offer unique opportunities for studying infectious diseases, genetic disorders, cancer and can even mimic embryonic developmental stages. Organoid research opens up new therapeutic options tailored for the individual or for small groups of patients.
Prof. Dr. Johannes Clevers is an immunologist and molecular geneticist who teaches at Utrecht University. He is a pioneer in the field of organoids. Clevers made important contributions to the understanding of how cancer develops. For example, he showed that stem cells and cancer cells use the same mechanisms. Since 2019, he has been one of the favorites to win a Nobel Prize.
In the context of the International Science Festival - Geist Heidelberg
Better understand and treat diseases
Geist Heidelberg Lecture
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